/ News / spotlight / 201301041705-the-year-in-review-2012-highlights-from-the-samuel-lunenfeld-research-institute

The Year in Review: 2012 Highlights from the Samuel Lunenfeld Research Institute

2013-01-04

In 2012, we witnessed not only key scientific breakthroughs in a number of diseases and treatment therapies, we also celebrated special moments like the appointments of some of our scientists to the Order of Canada and the Royal Society of Canada - moments which continue to show the world why the Lunenfeld is the place to be for award-winning scientists who are transforming the way we care for our patients.

Over the past year, Lunenfeld scientists made leading-edge discoveries in the prevention, detection and treatment of a variety of conditions and disorders, including cancer, kidney disease, women and infants’ health, and neurodegenerative disorders. Here are a few of our biggest highlights from 2012.
 

 

    JANUARY

January-Zinman

 

Dr. Bernie Zinman appointed to the Order of Canada

Dr. Bernie Zinman, Director, Leadership Sinai Centre for Diabetes, and Senior Investigator, Samuel Lunenfeld Research Institute, was appointed to the Order of Canada for his internationally-renowned achievements in diabetes patient care and research. Click here for more information.

 

    FEBRUARY

February-DNA

 

New discovery provides important new insight into how cells safeguard their genetic material

Mount Sinai Hospital researchers in the labs of Drs. Daniel Durocher and Frank Sicheri, as well as colleagues in Seattle, uncovered the structural mechanism behind DNA damage response cells. This discovery has deepened our understanding of genetic “protection” responses and will open the door to new, more sophisticated cancer therapies. Click here for more information.

 

    MAY

May-Siminovitch

 

Mount Sinai Hospital hosts an international symposium on personalized medicine

In May, Mount Sinai hosted an international symposium featuring world-renowned experts in personalized medicine. Thanks to continued innovative work by Dr. Kathy Siminovitch’s team at the Samuel Lunenfeld Research Institute, Mount Sinai has become a provincial leader in personalized medicine, attracting the attention of government and experts worldwide. Click here for more information.

 

    SEPTEMBER

September-Drucker September-Dennis

 

Dr. Dan Drucker and Dr. Jim Dennis elected to the Royal Society of Canada

Drs. Dan Drucker and Jim Dennis were among 19 life scientists elected to the Royal Society of Canada this year. Dr. Dennis has conducted ground breaking cancer research, furthering our understanding of the genetic and structural changes that promote metastasis as well as factors contributing to multiple sclerosis. Dr. Drucker has been recognized for his innovative work with glucagon-like peptides and DPP-4 inhibitors in the treatment of diabetes and intestinal disorders. Click here for more information.

 

    OCTOBER

October-Quagin

 

Discovery by Lunenfeld researchers has potential to impact treatments of kidney disease

Led by Dr. Susan Quaggin, a team of Lunenfeld researchers made an important discovery on the effects of a vital signalling protein in the kidney. This discovery has the potential to impact drug therapies and treatment for the more than 30,000 Canadians who suffer from kidney failure. Click here for more information.

 

    NOVEMBER

November-Briollais-Lye

Link between breastfeeding and childhood obesity discovered

With collaborators in Australia, Dr. Laurent Briollais, Principal Investigator of the study, his postdoctoral student, Dr. Taraneh Abarin, and Dr. Stephen Lye, discovered that the length of time a baby is breastfed can help reduce a child’s risk for obesity. Click here for more information.

 

 

November-mitosis

Breakthrough technology helps visualize cell division in unprecedented detail

Dr. Laurence Pelletier and his research team have used Mount Sinai’s super-resolution OMX microscope to conduct an innovative examination into the organization of centrosomes. This in-depth study allows for further understanding of cancer and conditions related to defects in chromosome segregation, such as Down’s syndrome. Click here for more information.

 

November-Zhen

 

Understanding human neurodegenerative disorders: what a worm’s got to do with it

A fascinating discovery by Dr. Mei Zhen and her team, published in the journal Neuron, is laying the groundwork for restoring co-ordination in movements for patients suffering from neurodegenerative disorders such as Huntington’s disease, Parkinson’s, ALS and others. The source of this discovery is the nervous system of a roundworm called C. elegans. Click here for more information.

 

    DECEMBER

December-Liang-Wrana-and-Val_Cell-Study

 

Identifying new ways to suppress the spread of cancer

Dr. Jeff Wrana and his team made a major discovery about the way that cancer spreads. The team found that proteins produced in normal cells near the environment of a cancer tumour influence the cancer’s ability to spread to other tissues of the body, a process called metastasis. This finding holds great potential to change the way cancer spreading will be treated in cancer patients. Click here for more information.

December-drug

 

FDA approves drug for rare gastrointestinal disorder developed by Lunenfeld scientist

Thanks to research by Dr. Daniel Drucker, Senior Lunenfeld Investigator, the FDA has approved a drug to treat patients with short bowel syndrome, a debilitating condition often associated with colon cancer and IBD patients. Click here for more information.

 

 

By Sandeep Dhaliwal

          
 LTRI
  About Us
   Senior Administration
   Research Committee
   Canada Research Chairs
   Technology Transfer
   Career Opportunities
  Researchers
   Investigators
    Dr. Irene L. Andrulis
    Dr. Rod Bremner
    Dr. Laurent Briollais
    Dr. Theodore J. Brown
    Dr. Shelley B. Bull
    Dr. Kieran Campbell
    Dr. Isabella Caniggia
    Dr. Robert F. Casper
    Dr. Graham L. Collingridge
    Dr. Sabine P. Cordes
    Dr. Joseph Culotti
    Dr. James Dennis
    Dr. Daniel J. Drucker
    Dr. Daniel Durocher
    Dr. Steven Gallinger
    Dr. Anne-Claude Gingras
    Dr. Pamela Goodwin
    Dr. Marc D. Grynpas
    Dr. Rayjean J. Hung
    Dr. Hartland W. Jackson
    Dr. Andrea Jurisicova
    Dr. Julia A. Knight
    Dr. Alexander G. Logan
    Dr. Stephen J. Lye
    Dr. Andras Nagy
    Dr. Michelle Nelson
    Dr. Kenichi Okamoto
    Dr. Laurence Pelletier
    Dr. Miguel Ramalho-Santos
    Dr. Frederick P. Roth
    Dr. Daniel Schramek
    Dr. Frank Sicheri
    Dr. Mark S. Silverberg
    Dr. Katherine Siminovitch
    Dr. Carolyn Steele Gray
    Dr. Ross Upshur
    Dr. Jim R. Woodgett
    Dr. Jeffrey Wrana
    Dr. Mei Zhen
    Dr. Bernard Zinman
   Clinician Scientists
    Dr. May Alarab
    Dr. Dominic Amato
    Dr. Amir Azarpazhooh
    Dr. Mrinalini Balki
    Dr. Chaim Bell
    Dr. Christine Brezden-Masley
    Dr. June C. Carroll
    Dr. Crystal Chan
    Dr. Martin C. Chang
    Dr. Kenneth Croitoru
    Dr. Ariel Dalfen
    Dr. Allan Detsky
    Dr. Brendan C. Dickson
    Dr. Rohan D. D’Souza
    Dr. Denice S. Feig
    Dr. Emer Finan
    Dr. John S. Floras
    Dr. Michael Fralick
    Dr. Shiphra R. Ginsburg
    Dr. Rebecca A. Gladdy
    Dr. Michael Goldberg
    Dr. Ellen Greenblatt
    Dr. Masoom A. Haider
    Dr. Jonathan J. Hunter
    Dr. Amna F. Husain
    Dr. Amish Jain
    Dr. Keith A. Jarvi
    Dr. Lianne P. Jeffs
    Dr. Jennie Johnstone
    Dr. Rita Kandel
    Dr. Edmond Kelly
    Dr. Edward C. Keystone
    Dr. James Khan
    Dr. John Kingdom
    Dr. Richard Kirsch
    Dr. Elena Kolomietz
    Dr. Caroline K. Kramer
    Dr. Stephen Lapinsky
    Dr. Shoo K. Lee
    Dr. Molyn Leszcz
    Dr. Susanna Mak
    Dr. Ann K. Malinowski
    Dr. Robert G. Maunder
    Dr. Taymaa May
    Dr. Allison McGeer
    Dr. Warren McIsaac
    Dr. Sangeeta Mehta
    Dr. Shikha Mittoo
    Dr. Ally Murji
    Dr. Kellie E. Murphy
    Dr. Geoffrey C. Nguyen
    Dr. Karel O'Brien
    Dr. Christian Pagnoux
    Dr. Claire Pain
    Dr. John Parker
    Dr. Bruce A. Perkins
    Dr. Allan Peterkin
    Dr. Aaron F. Pollett
    Dr. Paula Ravitz
    Dr. Albiruni A. Razak
    Dr. Ravi Retnakaran
    Dr. Robert H. Riddell
    Dr. Greg Ryan
    Dr. Joel Sadavoy
    Dr. Francisco J. Sanchez-Guerrero
    Dr. Amanda Selk
    Dr. Prakeshkumar Shah
    Dr. Vibhuti Shah
    Dr. Naveed Tahir Siddiqui
    Dr. Candice K. Silversides
    Dr. Daisy R. Singla
    Dr. Kim Tsoi
    Dr. Hillary A. Steinhart
    Dr. Carol Swallow
    Dr. Howard C. Tenenbaum
    Dr. Sharon L. Unger
    Dr. Chen Wang
    Dr. Virginia A. Wesson
    Dr. Lesley Wiesenfeld
    Dr. Rory Windrim
    Dr. Jay Wunder
    Dr. Alexandre Zlotta
   Staff Scientists
    Dr. Karen Colwill
    Dr. John Georgiou
    Dr. Gerald D. Gish
    Dr. Farzad Khalvati
    Dr. Colin Mckerlie
    Dr. Jinyi Zhang
   Associate Members / Scientists
    Dr. Gary D. Bader
    Dr. Bharati Bapat
    Dr. Marcus Bernardini
    Dr. Lisa D. Burry
    Dr. George S. Charames
    Dr. Mary Chiu
    Dr. Eleftherios P. Diamandis
    Dr. Sarah Ferguson
    Dr. Michael Glogauer
    Dr. Jack M. Goodman
    Dr. Tae Hart
    Dr. Johannes Keunen
    Dr. Sarina Isenberg
    Dr. Jordan Lerner-Ellis
    Dr. Zhong-Cheng Luo
    Dr. Stephen G. Matthews
    Dr. John R. McLaughlin
    Dr. Helen McNeill
    Dr. Massieh Moayedi
    Dr. Abdul Noor
    Dr. Ian M. Rogers
    Dr. Mike Tyers
    Dr. Pete Wegier
   Physician Directory
  Research Resources
   Our Research
   Expertise
  Training Centre
  News
   Spotlight
    Innovations in prostate cancer research during moustache season and beyond
    New genetic discoveries offer hope to IBD patients
    Diabetes: disease of the 21st century will affect approximately 500 million by 2030
    What does a worm’s nervous system tell us about disorders like Huntington’s Disease?
    The Year in Review: 2012 Highlights from the Samuel Lunenfeld Research Institute
    Millennials Help Scientists Transform Breast Cancer Research
    How Research Impacts Your Health
    2013 International Symposium: Frontiers in Diabetes Research
    $35 Million Gift from Larry and Judy Tanenbaum Launches Fundraising Drive for Endowment to Support Medical Research
    Director warns why we shouldn't neglect basic science in favour of applied science
    The anatomy of a major discovery
    Unravelling the mysteries of complex brain disorders
    LTRI Q&A: How do we predict breast cancer risk more effectively?
    Michal Zimmermann and his efforts to improve cancer drug efficacy
    Dheva Setiaputra
    Salomé Adam
   Discovery Corner
    Not your typical March Break: the life of an intern at the LTRI
  COVID-19
  Aside
   Slides relating to the recommendations of CANADA'S FUNDAMENTAL SCIENCE REVIEW