Dr. Carol Swallow — The Samuel Lunenfeld Research Institute

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Samuel Lunenfeld
Research Institute
Mount Sinai Hospital
Joseph and Wolf Lebovic Health Complex
60 Murray St, Box 42
Toronto ON M5T 3L9

Tel.: 416-586-4800

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Dr. Carol Swallow
ASSOCIATE MEMBER

Dr. Carol Swallow is a surgical oncologist and Head of the Division of General Surgery at Mount Sinai Hospital, who is committed to the improved management of patients with gastrointestinal cancer. Her focus is on innovative surgical techniques, with a strong emphasis on colon cancer and metastatic colon cancer to the liver.

She graduated from the University of Toronto Medical School, and trained in the General Surgery residency program at the University as a member of the Surgical Scientist Training Program, completing a PhD in cell biology and surgical sepsis. After this, she completed clinical fellowship training in Surgical Oncology at Memorial Sloan Kettering Cancer Center in New York.

Dr. Swallow’s areas of clinical expertise include advanced and recurrent colorectal cancer, retroperitoneal sarcoma, gastrointestinal stromal tumour, and gastric cancer. Her work, in collaboration with Lunenfeld Senior Investigator Dr. Jim Dennis, was instrumental in establishing the Sydney C. Cooper Program for the Prevention of Cancer—a novel program at Mount Sinai Hospital that is bridging the gap between fundamental research and clinical research.

Dr. Swallow is also an Associate Scientist at the Lunenfeld, and her research interests focus on cell cycle regulation, carcinogenesis and metastasis. Specifically, Dr. Swallow is investigating the role of a protein called fetuin and its role in the development and progression of cancer, as well as the gene Plk4, which is implicated in liver cancer. Drs. Swallow and Dennis are using screening methods to analyze patient tumour samples to assess how Plk4 contributes to the growth and spread of liver cancer.

Dr. Swallow is also a Professor in the Department of Surgery and Institute of Medical Science at the University of Toronto, with a cross appointment to the Department of Laboratory Medicine and Pathobiology.

She is Chair of the Royal College General Surgical Oncology Specialty Committee, and the President of the Canadian Society of Surgical Oncology, and is the author of 50 peer-reviewed papers.

Jul 05, 2011 05:05 PM

At a Glance

Dr. Swallow is a surgical oncologist and scientist who specializes in colorectal cancer.
Her clinical areas of expertise areadvanced and recurrent colorectal cancer, retroperitoneal sarcoma, gastrointestinal stromal tumours, and gastric cancer.
Dr. Swallow was instrumental in the establishment of Mount Sinai’s Sydney C. Cooper Program for the Prevention of Cancer.

Major Research Activities

Dr. Swallow is investigating the molecular and genetic factors underlying cancer and metastases. Her work includes genetic analyses of tumour samples to determine genetic signatures of disease, and if changes in gene expression occur with metastases.

Recent Publications

DuBayD, Lindsay T, Swallow CJ, McGilvray I: A cylindrical femoral vein panel graft for caval reconstruction. Journal of Vascular Surgery 2009: 49(1): pp 255-9.

Stotland P, Moozar K, Cardella J, Fleshner N, Sharir S, Smith AJ, Swallow CJ: Urologic complications of composite resection following combined modality treatment of colorectal cancer. Annals of Surgical Oncology 2009: 16(10): pp 2759-64.

Karanicolas PJ, Dubois L, Colquhoun PH, Swallow CJ, Walter SD, Guyatt GH: The more the better? The impact of surgeon and hospital volume on in-hospital mortality following colorectal resection. Annals of Surgery 2009: 249(6): pp 954-9.

Dubay D, Gallinger S, Hawryluck L, Swallow C, McCluskey S, McGilvray I: In situ hypothermic liver preservation during radical liver resection with major vascualr reconstruction. British Journal of Surgery 2009: 96(12): pp 1429-36.

Davidge K, Eskicioglu C, Lipa J, Ferguson P, Swallow C, Wright F: Qualitative assessment of patient experiences following sacrectomy. Journal of Surgical Oncology 2010: 101(6): pp 447-50.

Rosario CO, Ko MA, Haffani Y, Gladdy RA, Paderova J, Pollett A, Squire JA, Dennis JW, Swallow CJ: Plk4 is required for cytokinesis and maintenance of chromosomal stability. Proceedings of the National Academy of Sciences (USA) 2010: 107(15): pp 6888-93.

Kassam Z, MacKay H, Buckley CA, Fung S, Pintile M, Oza A, Brierley J, Swallow C, Cummings B, Knox J, Kim J, Wong R, Siu L, Feld R, Ringash J: Adjuvant chemoradiation for gastric cancer with infusional 5-fluorouracil and cisplatin: a phase I study. Current Oncology 2010: 17(4): pp 34-41.

Vergara-Fernandez O, Swallow CJ, Victor C, O'Connor BI, Yoon W, Gryfe R, MacRae HM, Cohen Z, McLeod, RS: Setting benchmarks for outcomes following surgery for colorectal cancer using quality of care indicators. Canadian Journal of Surgery 2010: 53(4): pp 232-240.

Peer-Reviewed (Accepted for Publication):

Soh SY, Dimaras H, Gupta A, Rushlow D, Swallow C, Crump M, Halliday W, Doyle JJ, Babyn P, Heon E, Gallie BL, Chan HSL: Adult ovarian retinoblastoma genomic profile distinct form prior childhood eye tumour. Archives of Ohthalmology (in press).

Non-Peer Reviewed:

Raut CP, Swallow CJ: Are radical compartmental resections for retroperitoneal sarcomas justified? Annals of Surgical Oncology 2010: 17(6): pp 1481-4.

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