Dr. John McLaughlin — The Samuel Lunenfeld Research Institute

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Dr. John McLaughlin
SENIOR INVESTIGATOR; PROFESSOR AT DALLA LANA SCHOOL OF PUBLIC HEALTH; RESEARCH ADVISOR AT PUBLIC HEALTH ONTARIO

Epidemiologist, Professor John McLaughlin is a leader in Canadian cancer research. He has published extensively and leads interdisciplinary teams in large, population-based studies to identify cancer causes and prevention strategies. In particular, he is interested in how the interaction of environmental and genetic factors leads to illness in the population. He is currently conducting studies related to colorectal, ovarian and other cancers, focusing on roles of both environmental and genetic factors, and as an active scientist, he has more than 160 peer-reviewed publications.

Dr. McLaughlin’s leadership extends well beyond his own group. He established and was the inaugural leader of the Prosserman Centre for Health Research at the Samuel Lunenfeld Research Institute, which is recognized for its leadership in molecular and genetic epidemiology. Researchers at the Prosserman Centre perform large-scale epidemiological studies of cancer and other important diseases, aiming to both make new discoveries and to develop new and better disease control strategies.

He works to improve cancer prevention and to promote health by applying existing knowledge and building new ways for prevention research to be done in Canada. For example, while serving as Vice President at Cancer Care Ontario, he directed teams that launched the Ontario Health Study, the Occupational Cancer Research Centre, and the nation’s first population-based colorectal screening program. As Professor in the Dalla Lana School of Public Health at the University of Toronto, he also teaches and supervises graduate students.

Samuel Lunenfeld
Research Institute
Mount Sinai Hospital
Joseph & Wolf Lebovic Health Complex
600 University Avenue
Toronto Ontario M5G 1X5

Tel: 416-586-4800 ext.8304
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Jul 13, 2009 04:20 PM

At a Glance

Dr. John McLaughlin studies cancer causes and prevention in populations
He is interested in how the interaction of environmental and genetic factors can lead to illness in the population
He is currently conducting studies related to colorectal, ovarian and other cancers
Dr. McLaughlin is also Research Advisor to Public Health Ontario

Major Research Activities

Our research team aims to discover and characterize environmental and genetic factors involved in the development of cancer, and to determine the impact of these factors in human populations. Inter-disciplinary teams conduct population-based studies under the direction of Dr. McLaughlin, with the ultimate aim of improving the prevention and early detection of cancer. These studies explore the relative contribution of genetic and environmental factors as causes of colorectal, ovarian, lung and other cancers. As a leader of population studies for Ontario and Canada, Dr. McLaughlin also strives to have research findings applied to reduce the burden of cancer in the population.

Recent Publications

McLaughlin JR, Risch H, Lubinski J, Moller P, Ghadirian P, Lynch H, Karlan B, Fishman D, Rosen B, Neuhausen S, Offit K, Kauff N, Domchek S, Tung N, Friedman E, Foulkes W, Sun P, Narod S and the Hereditary Ovarian Cancer Clinical Study Group. Risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations. Lancet Oncology 2007;8(1):26-34.

Brenner DR (graduate student), Hung RJ, Tsao M, Shepherd F, Johnston M, Narod S, Rubenstein W, McLaughlin JR. Lung cancer risk in never-smokers: A population-based case-control study of epidemiologic risk factors. BMC Cancer 2010; 10(1): 285: 1-9.

Sun ZY, Wang PP, Roebothan B, Buehler S, Zhao J, Zhu Y, Cotterchio M, Campbell P, Dicks E., McLaughlin J (co-senior author) and Parfrey P. Calcium and Vitamin D and risk of Colorectal Cancer: results from a large population-based case-control study in Newfoundland and Labrador and Ontario. Canadian Journal of Public Health 2011; 102(5):382-89.

McKay JD, et al. (large international consortium including McLaughlin J). Lung cancer susceptibility locus at 5p15.33. Nature Genetics 2008; 40(12):1404-6.

► Lunenfeld Research Repository

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