Personal tools
Dr. Rayjean Hung
You are here: Home → Researchers → Dr. Rayjean Hung

 

hung  

Dr. Rayjean J. Hung 
 INVESTIGATOR

Dr. Rayjean Hung conducts research into the molecular and genetic epidemiology of cancer, in particular tobacco-related cancers and childhood cancers. As an epidemiologist, she studies why and how cancer occurs with the ultimate goal of understanding and preventing the disease.

Dr. Hung joined the Institute in December of 2007, most recently from the University of California at Berkeley, where she also held the position of Visiting Researcher at the International Agency for Research on Cancer (IARC) in Lyon, France.

The international scope of her work allows Dr. Hung to provide scientists in Ontario with an important link to cancer research world-wide, and brings renewed attention to the study of cancer being done in the province.

Dr. Hung made headlines in 2008 for her role in an international study that uncovered, for the first time, an important genetic region associated with lung cancer risk. Dr. Hung was first author of a paper published in the most prestigious scientific journal Nature demonstrating that chromosome 15 is associated with lung cancer, and providing new clues on how smoking tobacco can cause this cancer. Lung cancer is the most common cause of cancer death worldwide, with more than 1 million cases diagnosed annually. It is also the most preventable, since, according to the World Health Organization, tobacco smoking is responsible for around 90% of all cases. The disease affects 20,000 Canadian lives annually and 80% of lung cancer patients die within five years.
 
Prosserman Centre for Health Research
Samuel Lunenfeld Research Institute
Mount Sinai Hospital
60 Murray Street
Toronto Ontario M5T 3L9
Tel: 416-586-4800 ext.4750
Send Email
 

 
Jul 15, 2009 05:15 PM

     

At a Glance

  • Dr. Hung was awarded the prestigious Cancer Care Ontario Research Chair in Population Studies
  • Dr. Hung’s research focuses on molecular and genetic epidemiology of cancer with ultimate goals of understanding how cancer develops
  • The current research topics include international studies of tobacco-related cancers and childhood cancers

 

 

Major Research Activities

Dr. Hung's research focuses on molecular and genetic epidemiology of cancer with ultimate goals of understanding cancer etiology and mechanism, and contributing to primary and secondary prevention. The current research topics in Dr. Hung's team include international studies of tobacco-related cancers and childhood cancers.

 

 

Selected Recent Publications

Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holcátová I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature. 2008;452(7187):633-7


McKay JD, Hung RJ, Gaborieau V, Boffetta P, Chabrier A, Byrnes G, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, McLaughlin J, Shepherd F, Montpetit A, Narod, S, Krokan HE, Skorpen F, Elvestad MB, Vatten L, Njolstad I, Axelsson T, Chen C, Goodman G, Barnett M, Loomis MM, Lubinski J, Matyjasik J, Lener M, Oszutowska D, Field JK, Liloglou T, Xinarianos G, Cassidy A, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P. Identification of gene region 5p15.33 as a novel lung cancer susceptibility locus using 5,800 lung cancer cases and 9,300 controls. Nat Genet. 2008 Dec;40(12):1404-6. [Joint first authors]


Wakefield J, De Vocht F, Hung RJ.  Bayesian Mixture Modeling of Gene-Environment and Gene-Gene Interactions. Genetic Epidemiology. In press. 2009

 

 

Document Actions
 
[RSS]