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Dr. John McLaughlin
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Dr. John McLaughlin 
 SENIOR INVESTIGATOR; VICE-PRESIDENT, POPULATION STUDIES & SURVEILLANCE, CANCER CARE ONTARIO

Epidemiologist Dr. John McLaughlin is a leader in Canadian cancer research. Dr. McLaughlin has published extensively and leads interdisciplinary teams in large, population-based studies to identify cancer causes and prevention strategies. In particular, he is interested in how the interaction of environmental and genetic factors can lead to illness in the population. He is currently conducting studies related to colorectal, ovarian and other cancers.

Dr. McLaughlin’s leadership extends well beyond his own laboratory. He established and was the inaugural leader of the Prosserman Centre for Health Research at the Samuel Lunenfeld Research Institute, which is recognized for its leadership in molecular and genetic epidemiology. Researchers at the Prosserman Centre perform large-scale epidemiological studies of cancer and other important diseases, aiming to both make new discoveries and to develop new and better disease control strategies.

He is also Vice President responsible for Population Studies and Surveillance at Cancer Care Ontario (CCO), the provincial government’s chief cancer advisor which manages cancer prevention, screening and clinical programs for Ontario. He was selected to lead the Ontario Health Study (www.ontariohealthstudy.ca), a major new cohort initiative that will involve 150,000 volunteers from across Ontario, with support from provincial and national agencies. Dr. McLaughlin is also a Professor in the Dalla Lana School of Public Health at the University of Toronto, where he teaches and supervises graduate students.

As a cancer researcher, Dr. McLaughlin aims to advance knowledge. As a leader of preventive oncology programs, he also works to apply existing knowledge to improve population-based cancer prevention and screening programs, with the ultimate goal of reducing the risk and burden of cancer in Ontario.

 

 
Samuel Lunenfeld Research Institute
Mount Sinai Hospital
Joseph & Wolf Lebovic Health Complex
600 University Avenue
Toronto Ontario M5G 1X5
Tel: 416-586-4800 ext.8304

 

 

Jul 13, 2009 04:20 PM

     

At a Glance

  • Dr. John McLaughlin studies cancer causes and prevention in populations
  • He is interested in how the interaction of environmental and genetic factors can lead to illness in the population
  • He is currently conducting studies related to colorectal, ovarian and other cancers
  • Dr. McLaughlin is also vice president of Population Studies & Surveillance at Cancer Care Ontario

 

 

Major Research Activities

Our research team aims to discover and characterize environmental and genetic factors that are involved in the development of cancer, and to determine the impact of these factors in human populations. Inter-disciplinary teams conduct population-based studies under the direction of Dr. McLaughlin, with the ultimate aim of improving the prevention and early detection of cancer. These studies explore the relative contribution of genetic and environmental factors as causes of colorectal, ovarian, lung and other cancers. As a leader of population studies and surveillance for Ontario, Dr. McLaughlin also strives to have research findings applied to reduce the burden of cancer in the population.

 

 

Recent Publications

McLaughlin JR, Risch H, Lubinski J, Moller P, Ghadirian P, Lynch H, Karlan B, Fishman D, Rosen B, Neuhausen S, Offit K, Kauff N, Domchek S, Tung N, Friedman E, Foulkes W, Sun P, Narod S and the Hereditary Ovarian Cancer Clinical Study Group. Risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations. Lancet Oncology 2007;8(1):26-34.

Campbell PT(graduate student), Cotterchio M, Dicks E, Parfrey P, Gallinger S, McLaughlin JR. Excess body weight and colorectal cancer in Canada: associations in subgroups of clinically defined familial risk of cancer. Cancer Epidemiology Biomarkers & Prevention. 2007; 16 (9): 1735-1744.

Hung R et al. (from an international consortium including JM). International Lung Cancer Consortium: Pooled analysis of Sequence Variants in DNA Repair and Cell Cycle Pathways. Cancer Epidemiology Biomarkers and Prevention 2008; 11:3081-4.

 

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