The Lunenfeld-Tanenbaum Research Institute
Donate Now - Mount Sinai Hospital Foundation of Toronto Lunenfeld QR code
Personal tools
Dr. Sean Cleary
Home Researchers Dr. Sean Cleary

Dr. Sean Cleary

 

Dr. Sean Cleary 
ASSOCIATE MEMBER 

Dr. Sean Cleary is a clinician-scientist at Mount Sinai Hospital and the University Health Network. His research interests are focused on the genetic epidemiology of liver, pancreas and colorectal cancer, and his clinical practice is in the surgical management of these malignancies. During his residency, Dr. Cleary obtained a Master's of Science in Cancer Genetics under the supervision of Dr. Steven Gallinger, and completed a MHSc in Public Health and Epidemiology in the Department of Public Health Sciences.
 
Dr. Cleary is focused on exploring how the risk of developing cancer is influenced by our genetic makeup as well as the environment around us. Individual genetic variants, either alone or in combination with other variants, can contribute small incremental changes to our cancer risk. Genetic factors can also influence our susceptibility to environmental factors that either increase, or decrease, our risk of cancer. Dr. Cleary is working to understand the relationship between genetic variation and environmental exposures, to help identify high-risk groups in our population and provide insight into the etiologic mechanisms of cancer.

 

Lunenfeld-Tanenbaum
Research Institute
Mount Sinai Hospital
Joseph and Wolf Lebovic Health Complex
60 Murray St, Box 42
Toronto ON M5T 3L9

Tel.: 416-586-4800

► Send Email
 

 

 

 

 

 

At a Glance

  • Dr. Sean Cleary is a clinician-scientist focused on the genetic epidemiology of liver, pancreas and colorectal cancer, as well as the surgical treatment of these malignancies.
  • He completed a fellowship in Pancreatic and Hepatobiliary Surgical Oncology and Transplantation at the Toronto General Hospital after finishing his General Surgery Residency training at the University of Toronto.
  • His research interests are focused on the genetic epidemiology of liver, pancreas and colorectal cancer, and his clinical practice is in the surgical management of these malignancies. 


 

Major Research Activities

  • Dr. Cleary's research to date has included characterization of the colorectal cancer risk associated with variants in the APC and Blm genes.
  • In collaboration with the Colon Family Registry, he studied the association between mutations in the MUYH gene and colorectal cancer.
  • His recent work has also included studying the associations between variants in carcinogen metabolism genes and smoking in colorectal and pancreatic cancer.

 



 

Recent Publications

 

 

Document Actions
Ontario Health Study Faculty of Medicine, University of Toronto. mitacs honorary partner

 

 
plone
       
 
   
spinner
Facebook popup Youtube popup Twitter popup RSS popup